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About
with GHK-Cu Copper Peptide + Apple Stem Cell
This moisturizer was built for skin in the menopause transition and beyond. GHK-Cu Copper Peptide and other hydrating ingredients visibly plump and firm while softening the look of fine lines for support that goes beyond surface-level moisture.
After 35, skin becomes drier, less firm, and less elastic, changes that are often linked to the estrogen decline of the menopause transition. The moisturizers that worked before often don't do enough anymore. Most hydrate the surface but can't support the loss of firmness underneath. Tripeptide Plumping Moisturizer was built for these changes; it nourishes beyond the surface, visibly plumps, and supports a firmer-looking texture.
GHK-Cu Copper Peptide, a copper-bound bioactive peptide, supports the appearance of firmer, more resilient skin. Apple stem cell extract adds concentrated antioxidants that help defend against environmental stress. Sodium hyaluronate draws and binds moisture into the skin for a visibly plumper complexion; niacinamide refines the look of tone and texture while supporting the skin barrier; and aloe, cucumber, chamomile, and panthenol soothe skin that is commonly more reactive at this stage of life.
Apply Tripeptide Plumping Moisturizer after your cleanser, serums, and eye cream and before applying SPF. For the best plumping and firming results, apply both morning and night.
Visible support for the dullness, dryness, and loss of elasticity that come with the menopause transition
Immediate results:
Long-term results:
This image is AI-generated and is intended solely to demonstrate product usage.
Results you’ll love, backed by science
Your complete system for great skin in every decade
These three key functions create healthy, beautiful, and resilient skin that maintains its look through the menopause transition and beyond.
Core
Cleanse, hydrate & preserve skin barrier function.
Defense
Protect against environmental stressors & toxins.
Renewal
Target visible signs of aging & skin damage.
Build out your routine.
Tripeptide Plumping Moisturizer is part of the Core line and pairs well with:
Core
Nourishing Cream CleanserStart your morning and evening routines with a gentle cleanse that preps skin to fully absorb every product that follows.
Core
HA + Peptide Repair SerumApply in the morning and evening before moisturizing to create a barrier serum layer and increase hydration.
Defense
Radiance C + Ferulic SerumPair in the morning for combined antioxidant and plumping support.
Tripeptide Plumping Moisturizer
Formulated with clinical precision and the ingredients your skin actually needs
Designed for skin in perimenopause to postmenopause
Physician-curated formula
Supports skin barrier function
Formulated with GHK-Cu Copper Peptide, the gold-standard copper peptide
Soothing botanical blend for dry or irritation-prone skin
A routine you’ll understand, for results you’ll see & feel
Skin in the menopause transition and beyond needs hydration, barrier support, and visible firmness. That's why the best formulas are peptide-forward. Copper peptides address the look of lost firmness that standard moisturizers can't. Tripeptide Plumping Moisturizer is physician-curated and formulated specifically for skin in this stage of life, pairing GHK-Cu Copper Peptide with niacinamide, sodium hyaluronate, and soothing botanicals.
Apple stem cell extract (Malus Domestica Fruit Cell Culture Extract) is a plant-derived ingredient created by culturing cells from apples in a lab. Despite the name, no stem cells are applied to your skin — plant and human cells aren't biologically compatible. The benefit comes from the concentrated antioxidants and phytonutrients those cultured cells produce. In this formula, it helps defend against the environmental stress, including pollution, UV exposure, and daily oxidative wear, that contributes to visible aging over time.
As estrogen declines, skin loses firmness faster than hydration alone can fix. GHK-Cu Copper Peptide is the rare moisturizer ingredient that addresses this directly to support the look of firmer, more resilient skin. Tripeptide Plumping Moisturizer pairs that peptide with sodium hyaluronate and panthenol to encourage skin that looks plumper and firmer with daily use.
No. Tripeptide Plumping Moisturizer uses Malus Domestica Fruit Cell Culture Extract, a plant-derived apple stem cell extract, not a medical stem cell therapy. What it delivers is the concentrated antioxidants those cultured cells produce, supporting healthy, more resilient-looking skin from perimenopause to postmenopause.
Yes, with consistent use, skin looks smoother and firmer. GHK-Cu Copper Peptide targets the loss of firmness that comes with estrogen decline, while sodium hyaluronate plumps skin from within.
Yes. Use morning and night after cleansing and serums, and follow with broad-spectrum sunscreen in the morning. Consistent twice-daily application delivers the formula's full plumping and firming benefits.
Yes, this product was designed for sensitive, reactive skin. As with any new product, patch test first if you have known sensitivities to copper or botanical extracts. The formula itself leans on aloe, cucumber, chamomile, and rose flower water, chosen specifically to calm the heightened sensitivity that comes with menopausal skin.
Our Core → Defense → Renewal system makes it simple. Cleanse and moisturize daily (Core). Protect with antioxidants and SPF (Defense). Add targeted treatments for the specific signs you most want to address (Renewal).
Winona's skincare is physician-curated and designed specifically for women in the menopause transition and beyond. Our line uses clinically-proven ingredients chosen for the visible changes that appear at this stage of life. While it was created with menopausal women in mind, the line serves as premier skincare for any woman over 30.
Winona’s skincare is an excellent complement to HRT but does not require HRT to work. Both can be used independently or in combination, as they serve different purposes. HRT addresses the root hormonal shifts, principally estrogen decline, that lead to a range of symptoms, including skin changes. While HRT can improve skin health, it is not a skin-specific treatment and cannot reverse existing changes like lost firmness, uneven tone, or dryness. Winona’s skincare is formulated specifically around these concerns to address skin barrier health, loss of hydration, accumulated sun damage, skin laxity, and collagen loss.
Yes. Subscriptions are discounted by $10 per order. You can cancel or modify your subscription anytime.
